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天然化合物

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カタログ番号	製品名	別名	ターゲット
TP2333	Cyclo(L-Pro-L-Tyr)		Others
	Maculosin is a secondary metabolite of fungi and bacteria.		Others
T10904	CWP232228		Wnt/beta-catenin
	CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...		Wnt/beta-catenin
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T1090	Perphenazine	Perphenazin,Etaperazine,Trilafon	CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T22443	Triglycidyl isocyanurate	Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI	Apoptosis
	Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk...		Apoptosis
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T23867	Cdc7-IN-7c	Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c	CDK
	Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.		CDK
T60226	CT52923		PDGFR
	CT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching an array of pathological dis...		PDGFR
T22136	PRL-3 Inhibitor I	PRL-3 Inhibitor,BR-1	Phosphatase , Others
	PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.		Phosphatase , Others
T27133	DCLX069	DCLX 069,DCLX-069	Histone Methyltransferase
	DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le...		Histone Methyltransferase
T9939	JMJD6 inhibitor WL12	2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033	Others
	JMJD6 inhibitor WL12 (ZINC6733033) is a first-in-class JMJD6 inhibitor and was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells, providing a small-molecule ...		Others
T18957	D-Ala-Lys-AMCA hydrochloride		Others
	D-Ala-Lys-AMCA hydrochloride is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into Caco-2 cells and liver cancer cell...		Others
T9945	MNK8	3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].		STAT
T62491	STAT3-IN-13		STAT
	STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which in...		STAT
TQ0141	Taltobulin	HTI-286,SPA-110	Apoptosis , Microtubule Associated
	Taltobulin (HTI-286) is a synthetic analog of the tripeptide cysteine, a microtubule protein inhibitor that inhibits liver tumor cell proliferation in vitro and tumor growth in vivo.Taltobulin is cytotoxic, induces mitot...		Apoptosis , Microtubule Associated
T0078L	Lapatinib ditosylate monohydrate	Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb	EGFR , Ferroptosis , Autophagy
	Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w...		EGFR , Ferroptosis , Autophagy
T0189L	Pemetrexed disodium	LY-231514,LY231514 disodium,Pemetrexed	Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
T14091	AC-73		Autophagy
	AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 incl...		Autophagy
T83658	SQLE-IN-1		Antifungal
	SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the...		Antifungal
T0976	Propoxur	Aprocarb,Propoxure,Baygon	AChR , Antifungal
	Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...		AChR , Antifungal
T69201	Lophenol
	Lophenol has potent inhibitory activity against human cancer cell lines such as liver cancer, nasopharyngeal and colon cancer cells.
T34757	Symphytine
	Symphytine is a natural inducer of hepatic tumors. Symphytine interacts with DNA in liver endothelial cells and hepatocytes, resulting in DNA damage, mutation induction, and cancer development.
T72740	N-Octyl caffeate
	n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.
T18958	D-Ala-Lys-AMCA TFA (375822-19-8 free base)	D-Ala-Lys-AMCA TFA	Others
	D-Ala-Lys-AMCA TFA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into Caco-2 cells and liver cancer cells.		Others
T61243	MAT2A-IN-5
	MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative a...
T61672	MAT2A-IN-7
	MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effect...
T25611	Lanatoside	Lantoside,ABC lanatoside complex
	Lanatoside is an FDA-approved cardiac glycoside that has been identified as a candidate anti-dengue compound. It has also been found to promote atherosclerosis. It also has anti-tumor activity, inhibiting the growth of c...
T37584	Tryptoquivaline D
	Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer ...
T18959	D-Ala-Lys-AMCA		Others
	D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells.		Others
T78526	4A3-SC8		Others
	4A3-SC8 is a modular, degradable dendrimer facilitating the extension of survival in aggressive liver cancer models through the delivery of small RNAs [1].		Others
T27816	Leucinostatin	A 20668,A20668,A-20668
	Leucinostatin is a peptide mycotoxins that have some potent effects on liver cells after oral administration. Leucinostatin is used as both antimicrobial and antitumor agents through interactions with the membrane phosph...
T82458	Epigenetic factor-IN-1		Sirtuin
	Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1].		Sirtuin
T63975	MAT2A-IN-1
	MAT2A-IN-1 is a potent inhibitor of MAT2A and is capable of proliferative activity in MTAP-deficient cancer cells. MAT2A is expressed at unusually high levels in several tumour types, including gastric, colon, liver and ...
T69758	Flutamide-d7
	Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted ...
T61801	HIV-1 inhibitor-35
	HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates in...
T79594	COX-1/2-IN-5		COX
	COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity by inhibiting liver cancer HepG2...		COX
T83433	1D228		c-Met/HGFR
	1D228, a c-Met/TRK inhibitor with antitumor properties, suppresses cyclin D1 to precipitate G0/G1 arrest, thereby inhibiting proliferation and migration of cancer cells. This compound is applicable in researching gastric...		c-Met/HGFR
T35809	C20 Sphingomyelin (d18:1/20:0)
	C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlate...
T79919	S-Adenosyl-L-methionine (1,4-butanedisulfonate)	Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)	Endogenous Metabolite
	S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for its significant antidepressant properties. Additionally, it plays anti-pr...		Endogenous Metabolite
T79373	A3AR agonist 2		Adenosine Receptor
	Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato...		Adenosine Receptor
T72861	(6R)-ML753286
	'(6R)-ML753286, an isomer of ML753286, is an orally active, selective Breast Cancer Resistance Protein (BCRP) inhibitor, demonstrating an IC50 of 0.6 μM. It exhibits high permeability and low to medium clearance in roden...
T71097	DC-120
	DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT ...
T82617	D-Ala-Lys-AMCA TFA
	D-Ala-Lys-AMCA TFA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate characterized by its emission of blue fluorescence. It has been demonstrated through fluorescence analysis that this compound can be tra...
T35978	Benastatin A
	Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme).2Benast...
T69035	Camostat free base
	Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or...
T61990	Topoisomerase I/II inhibitor 3
	Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell prolif...
T72997	HIF-2α-IN-7
	HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC 50 value of 6 nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer , liver ...
T79359	Anticancer agent 147		Ferroptosis
	Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS), and malondialdehyde (MDA), enhances endoplasmic reticulum ...		Ferroptosis
T79372	A3AR agonist 1		Adenosine Receptor
	A3AR Agonist 1 (Compound 12), with a Ki of 25.8 nM, is a potent A3 adenosine receptor (A3AR) agonist that promotes β-arrestin2 recruitment with an effective concentration (EC50) of 5.17 nM. It serves as a research tool i...		Adenosine Receptor
T79798	PHD-IN-2		HIF/HIF Prolyl-Hydroxylase
	PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 μM. It is applicable for research purposes acro...		HIF/HIF Prolyl-Hydroxylase

Compounds

Target: Wnt/beta-catenin

SC-236

T8505

Synonym: Sc 236

Target: Apoptosis, COX, PPAR

Perphenazine

T1090

Synonym: Perphenazin,Etaperazine,Trilafon

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Triglycidyl isocyanurate

T22443

Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI

Target: Apoptosis

Amantadine hydrochloride

T1406

Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Cdc7-IN-7c

T23867

Synonym: Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c

Synonym: PRL-3 Inhibitor,BR-1

Target: Phosphatase, Others

DCLX069

T27133

Synonym: DCLX 069,DCLX-069

Target: Histone Methyltransferase

JMJD6 inhibitor WL12

T9939

Synonym: 2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033

Target: Others

D-Ala-Lys-AMCA hydrochloride

Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

Synonym: HTI-286,SPA-110

Target: Apoptosis, Microtubule Associated

Lapatinib ditosylate monohydrate

T0078L

Synonym: Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb

Target: EGFR, Ferroptosis, Autophagy

Pemetrexed disodium

T0189L

Synonym: LY-231514,LY231514 disodium,Pemetrexed

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Synonym: Aprocarb,Propoxure,Baygon

Target: AChR, Antifungal

D-Ala-Lys-AMCA TFA (375822-19-8 free base)

T18958

Synonym: D-Ala-Lys-AMCA TFA

Synonym: Lantoside,ABC lanatoside complex

Synonym: A 20668,A20668,A-20668

Target:

Epigenetic factor-IN-1

C20 Sphingomyelin (d18:1/20:0)

T35809

Synonym:

Target:

S-Adenosyl-L-methionine (1,4-butanedisulfonate)

T79919

Synonym: Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)

Target: Endogenous Metabolite

A3AR agonist 2

T79373

Synonym:

Target: Adenosine Receptor

Topoisomerase I/II inhibitor 3

Target: Adenosine Receptor

PHD-IN-2

T79798

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase

カタログ番号	製品名	別名	ターゲット
T5S1923	Schisandrin C	Schizandrin-C,Wuweizisu-C	Apoptosis , Others , Virus Protease
	Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.		Apoptosis , Others , Virus Protease
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
TN1599	Eburicoic acid	Eburicoicacid,MFCD00238594,ZINC4655149	Antioxidant , TNF , NOS , NO Synthase , CCR , Immunology/Inflammation related
	Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in studies about anti-liver cancer.
TQ0065	Pseudobufarenogin	ψ-Bufarenogin	Others
	Pseudobufarenogin (ψ-Bufarenogin), a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.		Others
TN1143	1-O-Acetyl britannilactone		Apoptosis , Antibiotic
	1-O-Acetyl britannilactone is an agricultural fungicide that induces apoptosis and can be used in studies of liver injury and cancer.		Apoptosis , Antibiotic
TN5770	Gingerenone A		Nrf2
	Gingerenone A is an effective Nrf2-Gpx4 activator. It is a small molecule compound isolated from ginger. It has anti-cancer activity, can prolong the cell cycle of cancer cells, and can inhibit dextran sodium sulfate (DS...		Nrf2
T5S0018	Betulonic acid	(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite , HSV
	1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh...		Parasite , HSV
TN2272	Tigloylgomisin H		Nrf2
	Tigloylgomisin H represents a potential liver cancer prevention agent, it can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells, it functions as a novel monofunctional inducer ...		Nrf2
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T5S0754	Isoquercetin	3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside	NF-κB , Wnt/beta-catenin , NO Synthase
	1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ...		NF-κB , Wnt/beta-catenin , NO Synthase
T37067	9-hydroxy Stearic Acid		HDAC
	9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (...		HDAC
T6677	Sophocarpine		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
TN2507	1,6,7-Trihydroxyxanthone		DNA/RNA Synthesis
	1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.		DNA/RNA Synthesis
T2S2104	Sinigrin hydrate	Sinigrin monohydrate,Allylglucosinolate monohydrate	Antibacterial
	Sinigrin hydrate (Allylglucosinolate monohydrate) has antimicrobial activity. Sinigrin hydrate (Allylglucosinolate monohydrate) exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in...		Antibacterial
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran...
TN2308	Wilfortrine		BCL
	Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression.		BCL
TN5013	Shizukaol D		AMPK
	Shizukaol D exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway. Shizukaol D may be used to treat metabolic syndrome, it induces mitochondrial...		AMPK
TN4291	Isofuranodiene		IL Receptor , NOS
	Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting...		IL Receptor , NOS
TN4194	Heliangin		IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor
	Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-ÎºB pathway on LPS-induced RAW 264.7 cells. Heliangin has anti-cancer activity, it exhibits cytotoxic...		IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in...
TN4223	Homopterocarpin		Antifection
	Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribu...		Antifection
T36000	3-Hydroxyterphenyllin
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

天然物製品

Schisandrin C

T5S1923

Synonym: Schizandrin-C,Wuweizisu-C

Target: Apoptosis, Others, Virus Protease

Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Target: Others

Eburicoic acid

TN1599

Synonym: Eburicoicacid,MFCD00238594,ZINC4655149

Target: Antioxidant, TNF, NOS, NO Synthase, CCR, Immunology/Inflammation related

Pseudobufarenogin

TQ0065

Synonym: ψ-Bufarenogin

Target: Others

1-O-Acetyl britannilactone

TN1143

Synonym:

Target: Apoptosis, Antibiotic

Synonym: (+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Isoquercetin

T5S0754

Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside

Target: NF-κB, Wnt/beta-catenin, NO Synthase

9-hydroxy Stearic Acid

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

1,6,7-Trihydroxyxanthone

TN2507

Synonym:

Target: DNA/RNA Synthesis

Sinigrin hydrate

T2S2104

Synonym: Sinigrin monohydrate,Allylglucosinolate monohydrate

Target: Antibacterial

1,3,9-Trimethyluric acid

Target: IL Receptor, NOS

Heliangin

TN4194

Synonym:

Target: IL Receptor, TNF, NF-κB, MAPK, Prostaglandin Receptor

Cudratricusxanthone A

3-Hydroxyterphenyllin

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01091	CHD1L Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catal...
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPK-01477	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01436	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01478	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01417	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01520	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01521	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01484	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01483	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01482	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01519	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01515	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01132	PRL-1/PTP4A1 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is ...
TMPY-04205	AGR3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat...
TMPY-02622	Aldolase B Protein, Human, Recombinant (GST)	Human	E. coli
	The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed...
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPY-06226	SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like ...
TMPJ-01262	UPRT Protein, Human, Recombinant (His)	Human	E. coli
	UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o...
TMPY-02386	PTP4A2 Protein, Human, Recombinant (GST)	Human	E. coli
	PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PR...
TMPK-00336	GPC3 Protein-VLP, Human, Recombinant	Human	E. coli
	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ...
TMPY-02426	UBE2D1 Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up...
TMPK-00337	GPC3 Protein-VLP, Human, Recombinant (aa 438-554)	Human	HEK293 Cells
	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ...
TMPY-02757	TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext...
TMPY-06821	THRB Protein, Human, Recombinant (His)	Human	E. coli
	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
TMPY-02100	TEM7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin fa...
TMPY-02796	KIAA0101 Protein, Human, Recombinant (His)	Human	E. coli
	KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA bind...
TMPJ-01212	ULBP-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2...

CHD1L Protein, Human, Recombinant (His & SUMO)

TMPH-01091

Species: Human

Expression System: E. coli

MMP-12 Protein, Human, Recombinant (catalytic domain)

TMPY-02869

Species: Human

Expression System: E. coli

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01477

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01436

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01478

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01417

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01520

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01521

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

TMPK-01484

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01483

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01482

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01519

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

TMPK-01515

Species: Human

Expression System: HEK293 Cells

PRL-1/PTP4A1 Protein, Human, Recombinant (His)

TMPK-01132

Species: Human

Expression System: E. coli

AGR3 Protein, Human, Recombinant (mFc)

TMPY-04205

Species: Human

Expression System: HEK293 Cells

Aldolase B Protein, Human, Recombinant (GST)

TMPY-02622

Species: Human

Expression System: E. coli

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

TMPY-06226

Species: Cynomolgus

Expression System: HEK293 Cells

UPRT Protein, Human, Recombinant (His)

TMPJ-01262

Species: Human

Expression System: E. coli

PTP4A2 Protein, Human, Recombinant (GST)

TMPY-02386

Species: Human

Expression System: E. coli

GPC3 Protein-VLP, Human, Recombinant

TMPK-00336

Species: Human

Expression System: E. coli

UBE2D1 Protein, Human, Recombinant (His)

TMPY-02426

Species: Human

Expression System: E. coli

GPC3 Protein-VLP, Human, Recombinant (aa 438-554)

TMPK-00337

Species: Human

Expression System: HEK293 Cells

TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)

TMPY-02757

Species: Human

Expression System: HEK293 Cells

THRB Protein, Human, Recombinant (His)

TMPY-06821

Species: Human

Expression System: E. coli

TEM7 Protein, Human, Recombinant (His)

TMPY-02100

Species: Human

Expression System: HEK293 Cells

KIAA0101 Protein, Human, Recombinant (His)

TMPY-02796

Species: Human

Expression System: E. coli

ULBP-1 Protein, Mouse, Recombinant (His)

TMPJ-01212

Species: Mouse

Expression System: HEK293 Cells

カタログ番号	製品名
L2193	Anti-Liver Cancer Compound Library	1787 compounds
	1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L5510	Drug-induced Liver Injury (DILI) Compound Library	1001 compounds
	A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening；
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L2550	Glutamine Metabolism Compound Library	565 compounds
	A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L4600	Selected Plant-Sourced Compound Library	3048 compounds
	A unique collection of 3048 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-Liver Cancer Compound Library

L2193

Compounds: 1787

Drug-induced Liver Injury (DILI) Compound Library

L5510

Compounds: 1001

AMPK-Targeted Compound Library

L1120

Compounds: 80

Glutamine Metabolism Compound Library

L2550

Compounds: 565

Selected Plant-Sourced Compound Library

L4600

Compounds: 3048